Abbiategrasso Brain Bank Protocol for Collecting, Processing and Characterizing Aging BrainsTino Emanuele Poloni *1,4, Valentina Medici *1, Arenn Faye Carlos 1, Annalisa Davin 2, Arcangelo Ceretti 1, Michela Mangieri 1, Paola Cassini 1,4, Roberta Vaccaro 3, Daniele Zaccaria 3, Simona Abbondanza 3, Matteo Bordoni 5, Valentina Fantini 2,6, Elena Fogato 7, Cristina Cereda 5, Mauro Ceroni 8, Antonio Guaita 1,2,3
1Department of Neurology and Neuropathology, Golgi-Cenci Foundation, 2Laboratory of Neurobiology and Neurogenetic, Golgi-Cenci Foundation, 3Department of Neuropsychology and Social Sciences, Golgi-Cenci Foundation, 4Department of Rehabilitation, ASP Golgi-Redaelli Geriatric Hospital, 5Genomic and Post-Genomic Center, IRCCS Mondino Foundation, 6Department of Brain and Behavioral Sciences, University of Pavia, 7Department of Pathology, ASP Golgi-Redaelli Geriatric Hospital, 8Department of Neurological Science, IRCCS Mondino Foundation, University of Pavia
This protocol describes a method to track individual brain-aging trajectories through a brain donation program and proper characterization of brains. Brain donors are involved in a long-term longitudinal study including serial multi-dimensional assessments. The protocol contains a detailed description of brain processing and an accurate diagnostic methodology.
